Enable Cheminformatics and Bioinformatics in Microsoft Office

Cambridge, MA: Scilligence, a leading innovator of scientific software solutions, is thrilled to unveil HELM technology in TouchMol4Office (TM4O). 

TM4O represents an advancement in the realm of cheminformatics and bioinformatics within the Microsoft Office suite, providing researchers and professionals with a comprehensive platform for interfacing with internal and external databases while working seamlessly in applications like Excel, Word, and PowerPoint.

TM4O empowers users with powerful structure search capabilities, advanced informatics for biologics and conjugates, and now HELM support making it an indispensable tool for professionals working in the fields of chemistry, biology, and pharmaceuticals.

Empowering Chem-Bioinformatics within MS Office
Unleash the potential of MS Office with seamless integration of advanced chem-bioinformatics capabilities. This groundbreaking enhancement opens up a world of possibilities for professionals in the scientific and research communities.

Harnessing Macromolecules through HELM 
Embrace the future of scientific research with MS Office’s built-in support for macromolecules by utilizing HELM. Additionally, you have the option to integrate, unlocking access to exclusive HELM monomer libraries and taking your research to new heights.

Effortless Integration with Back-End Databases
Breakdown data silos and improve your research efficiency with TM4O’s ability to seamlessly connect with back-end databases. Now, you can effortlessly convert CAS numbers and registration IDs into molecular structures from diverse data sources, streamlining your workflow like never before.

With the enablement of HELM in TM4O, Scilligence aims to allow scientists to easily and quickly create complex macromolecules by using an industry-standard notation, making it an indispensable asset for researchers, scientists, and professionals across various industries.

“TouchMol4Office with the enablement of HELM technology will empower scientists to explore a wide variety of therapeutics modalities right inside Microsoft Office applications, a daily staple in research environments”, says Jinbo Lee, PhD, CEO at Scilligence Corporation.

RegMol 6.1.0 Release

Scilligence RegMol is a web-based registration database and assay data repository for biologics, small molecules, and conjugates. Some of RegMol’s many offerings include a powerful structure and bio-sequence search, batch registration, assay protocol management, and data mining analytics. RegMol’s comprehensive and easy-to-deploy platform empowers centralized data management and collaborations for life science research and development.

RegMol 6.1.0 includes the following improvements and changes:

  • Improved HELM Registration
  • New Assay Raw File and Plate Management
  • Improved Curve Fitting
  • New Assay Pivot function using Assay View
  • Revamped Admin menu
  • Bug Fixes

ELN 6.1.0 Release

Scilligence ELN (Electronic Laboratory Notebook) is a powerful platform for facilitating internal R&D and managing external collaborations. It comes with advanced informatics for biologics and small molecules, thus also supports conjugates such as antibody-drug conjugates (ADCs). Our ELN supports all disciplines of research including medicinal chemistry, process chemistry, bioassays, HTS, in vivo pharmacology, and toxicology. Widely adopted by industry and academic institutions, Scilligence ELN is easy to use, integrate, and deploy across all platforms.

Scilligence ELN 6.1.0 includes the following changes and improvements:

  • Improved Co-Author function
  • Improved Multi-factor Authentication (MFA)
  • Improved Flex-Form
  • Improved Form Manager
  • Improved Invention Management
  • Improved Final Report Module
  • ELN-in-Office integration
  • Revamped Admin menu
  • Bug fixes

New Office in San Francisco

Scilligence is pleased to announce the grand opening of its San Francisco office on February 17th, 2020! Our new location is 395 Oyster Point Blvd, Suite 209, San Francisco. We look forward to better serving our clients in the West Coast.

Our colleagues will be at Bio-IT West/Tri-Con (Booth #824) from March 1-4. Stop by and ask about our integrated solutions for life science R&D or about our open positions in California! Reach out to Scilligence at [email protected] to request a discounted session pass or a FREE pass for networking events and the plenary keynotes (including speaker Eric Topol).

Scilligence 6.5 Release Notes

ELN 6.5

  1. Shared notebook feature allows project members to create experiments and collaborate in a single notebook.

RegMol 6.5

  1. Improved API Key management allows customers to use RESTful APIs more easily and securely.
  2. Batch Explorer UI has been improved with pagination and more options for sorting and filtering data.
  3. Cart feature has access to many more data fields and enable better configuration/customization of data table for exportation into SDF, Excel, or csv.

Inventory 6.5

  1. Bulk import or update location function allows users to easily configure their location tree by importing an Excel file as well as make changes to existing location trees.
  2. Improved access control logic and documentation for management and customization of user roles.
  3. New plate history tracking allows users to record an audit trail for assay plate
  4. Improved compound management with plate scanner allows users to automatically create changes and calculations within a plate.
  5. Users now have the ability to change a location and sub-location so that containers can no longer be added to full locations.

PMF 6.5

  1. Improved Gantt chart for managing tasks and actions
  2. Multiple users can now edit large documents simultaneously with new Collaborate Editing Document (CED) feature
  3. Copy and download options added to projects and tasks for more flexibility

All Modules

  1. Updated JavaScript PDF viewer allows more flexibility for previewing experiments and documents
  2. Improved API Key management allows customers to use RESTful APIs more easily and securely.

Scilligence 6.6 Release Notes

ELN 6.6

1. Shared Notebooks
– Users can share notebooks like co-authored experiments
– Owner can rename a shared notebook

2. Improved Formulation Templates

3. Improved HELM functionality
– Support HELM repeating units
– Able to expand HELM nodes
– Improved HELM monomer replacement

4. Summary of plate experiments details
– Thumbnail for plate map
– Display number of assay plates and compounds
– Display submitted assay results

5. Improved audit trail
– Changes to experiment and notebook names tracked
– All witnesses included in experiment export

6. Fixed MF/MW calculations
– Small Library form automatically calculates
– MF updates correctly when structure changes and salt remains

7. User functionalities
– Ability to batch export user information
– No refresh needed when add users, appear automatically in UI

8. Improved re-fitting of QC Curve data in the Dose Response Form

Inventory 6.6

1. CAS Integration and Improvements
– Name to structure using CAS
– Automatic CAS and structure generation
– Up to date CAS Registration numbers
– Search structures via with CAS

2. Bulk Import
– Automatic CAS lookup during bulk import
– User experience improvements
– Ability to create new locations during bulk import

3. New Role – Purchase Stockroom
– Restricted role that can import product/lots/contains and change container location
– Role cannot modify in stock products

4. Access control
– New customization functions such as restriction based on site and department

5. Compound management
– Increased search control
– Improved search display

PMF 6.6

1. Improved CED Editing
2. Improved Gantt Charts
3. Improved Project Member Management

Focus 6.6

1. Ability to Synchronize RegMol Assays and Projects
2. Ability to Upload Data Using Files
3. Improved Filtering
4. Improved Sorting for Multiple Fields
5. Improved SAR Analysis
6. Improved Charting
7. Ability to Download Data

Scilligence 6.7 Release Notes

ELN v6.7.0 Release Notes

  1. Hybrid Free Form – only actual data can be pushed to RegMol.
  2. Improved Registration and Inventory integration
  3. Improved Study Report
  4. Updated Protein Purification template
  5. Improve Curve Assay template
  6. Improve security integration, including OKTA and Azure
  7. New file previewer
  8. Improved HELM features
  9. JSDraw supports Pictures
  10. Able to set colors to individual HELM monomers

6.7.0 Inventory Release Notes

  1. Improved compound management workflow
  2. Improved searching
  3. CAS integration
  4. Improved compound requisition workflow
  5. Improved bulk importing

 Release Notes for RegMol

  1. Improved bulk registration
  2. Improved admin tools on data curation
  3. Improved chirality check
  4. Support parent/batch synonyms
  5. Improved HELM registration
  6. Clean up for HELM-atom/bond hybrid structures


  1. Improved workflow engine
  2. Improved document management
  3. New file previewer


  1. New file previewer
  2. Improved RESTful APIs

Scilligence 6.8 Release Notes

ELN 6.8.0 Release Notes

  1. User FunctionalitiesError ReportingELN FormsDose Response CurveSecurityDisplayGeneral Fixes
  2. Inventory 6.8.0  Release Notes
  3. Compound Management ImprovementsCart ImprovementsContainers ImprovementsCustomization CapabilitiesLanguage ImprovementsAdmin capability improvementCompound Requisition improvements
  4. RegMol 6.8.0 Release Notes
  5. Registration ImprovementsExplorer ImprovementsAssay View and Assay ImprovementsHELM to Structure OptimizationRegMol and Inventory IntegrationAdmin and Security Features Improvement

Scilligence 6.6 Release Notes

Scilligence ELN 6.6.0

  1. Shared Notebooks
    1. Users can share notebooks like co-authored experimentsOwner can rename a shared notebook
    Improved Formulation TemplatesImproved HELM functionality
    1. Support HELM repeating unitsAble to expand HELM nodesImproved HELM monomer replacement
    Summary of plate experiments details
    1. Thumbnail for plate mapDisplay number of assay plates and compoundsDisplay submitted assay results
    Improved audit trail
    1. Changes to experiment and notebook names trackedAll witnesses included in experiment export
    Fixed MF/MW calculations
    1. Small Library form automatically calculatesMF updates correctly when structure changes and salt remains
    User functionalities
    1. Ability to batch export user informationNo refresh needed when add users, appear automatically in UI
    Improved re-fitting of QC Curve data in the Dose Response Form
  2. Scilligence Inventory 6.6.0
  3. CAS Integration and Improvements
    1. Name to structure using CASAutomatic CAS and structure generationUp to date CAS Registration numbersSearch structures via with CAS
    Bulk Import
    1. Automatic CAS lookup during bulk importUser experience improvementsAbility to create new locations during bulk import
    New Role – Purchase Stockroom
    1. Restricted role that can import product/lots/contains and change container locationRole cannot modify in stock products
    Access control
    1. New customization functions such as restriction based on site and department
    Compound management
    1. Increased search controlImproved search display
  4. Scilligence PMF 6.6.0
  5. Improved CED EditingImproved Gantt ChartsImproved Project Member Management
  6. Scilligence Focus 6.6.0
  7. Ability to Synchronize RegMol Assays and ProjectsAbility to Upload Data Using FilesImproved FilteringImproved Sorting for Multiple FieldsImproved SAR AnalysisImproved ChartingAbility to Download Data

Scilligence is now ISO 27001 Certified!

Scilligence Corporation, the leading provider of a unified informatics platform for small molecules and biologics, is now ISO 27001 certified. 

Certification was achieved after the successful completion of an 8-month audit.ISO 27001 is the accepted global benchmark for demonstrating your information security management system (ISMS). This accreditation ensures that we comply with the best practices in information technology and demonstrates our ongoing efforts toward maintaining information security.We strive to fulfill the expectations customers have in our security standards, and compliance with this globally recognized certification confirms our dedication to protecting data.About ScilligenceScilligence is an innovation leader in web-based cheminformatics and bioinformatics solutions for life sciences R&D. The Scilligence system is built with proprietary technologies to support biologics and small molecules in a unified platform, making it a flexible solution for a variety of research workflows. Scilligence’s informatics solutions include a variety of modules for data management that can be utilized as separate applications or as a fully integrated system. Its tools have been widely adopted by pharmaceutical, biotech, chemical industries, universities, research institutes, and government agencies.