Chemical.AI-Scilligence Launched their Strategic Cooperation to Co-develop ELN-based Data Integration

Chemical.AI, a high-tech company empowering chemistry with AI and ML, announced a strategic partnership with Scilligence, a web-based informatics solution provider for R&D. The two parties will co-develop high-efficiency data integration on Scilligence’s ELN with Chemical.AI’s leading AI-empowered route design systems (Retrosynthesis, forward synthesis, synthetic accessibility score, etc.), in a bid to enable Scilligence’s ELN users to search and utilize the data in their ELNs and molecular building block libraries with Chemical.AI’s route design systems.

Organic synthesis plays a key role in the R&D fields of pharmaceuticals, new materials, chemicals and other related industries. In the past, because of the diversity and complexity of organic reactions, the efficiency of organic synthesis strongly relied on chemists’ knowledge and expertise which is difficult to improve. Chemical.AI’s unique AI-aided route design systems can provide chemists with novel, feasible, and diversified synthetic routes. By helping them search and reuse internal data and experiences, such as ELNs and BB libraries, chemists can save their exploration time and broaden their skill-set. Scilligence’s ELN aimes to significantly strengthen internal teamwork, knowledge sharing, and information management of pharmaceutical enterprises and enhance their R&D outputs. The data integration of Chemical.AI’s route design systems into Scilligence’s ELN will significantly enhance the R&D efficiency of organic synthesis and its related industries.

“Nowadays, AI has gradually penetrated  nearly every field of our lives and work, and computer application programs based on big data and artificial intelligence are starting to show great potential in assisting researchers in chemical synthesis route design.” Said Dr. Ning Xia, founder and CEO of Chemical.AI, “We are pleased to collaborate with Scilligence to develop ELN-based data integration to leverage our respective strengths to further advance data reuse, knowledge sharing, and research innovation, accelerate the application of data integration in the pharmaceutical R&D process and realize win-win cooperation.”

“Only by leveraging the most cutting-edge and practical informatics research and development can we effectively promote scientific output in the biomedical field. We hope to have more opportunities to integrate our solutions more deeply into user workflows to enhance the efficiency of scientific research activities. Scilligence is pleased to collaborate deeply with Chemical.AI in data integration based on ELN to automate, accelerate and intelligentize chemical synthesis and drug R&D.” Said Jinbo Lee, CEO of Scilligence.

About Chemical.AI

Chemical.AI, an R&D technology company empowering chemistry with AI that uses artificial intelligence technology, chemical big data and machine learning to develop toolkit that dramatically improves the efficiency of chemical research, is committed to building an intelligent planning platform for compounds to reshape the future of chemistry.

Chemical.AI was founded in Wuhan in 2018, and its subsidiary, Shanghai Chemiscal Biotech Co., Ltd. was established in 2021, aiming to provide intelligent and automotive synthesis service. Chemical.AI’s team consists of cheminformatics specialists, chemical synthesis experts and talented IT professionals. Up to now, Chemical.AI has successfully provided technical services for many famous pharmaceutical companies and CROs at home and abroad, and has launched in-depth cooperation in the directions of synthetic route design, process route design, synthetic service, etc.

About Scilligence

Scilligence is an innovation leader of web-based cheminformatics and bioinformatics solutions for life sciences R&D. The Scilligence system is built with proprietary technologies to support both biologics and small molecules in a unified platform, making it a flexible solution for a variety of research workflows. Scilligence’s informatics solutions include a variety of modules for data management that can be utilized as separate applications or as a fully integrated system. Its tools have been widely adopted by pharmaceutical, biotech and chemical industries, universities, research institutes, and government agencies. Scilligence is the developer of the HELM (Hierarchical Editing Language for Macromolecules) Web Editor which works to further standardize HELM notation and facilitate the exchange of information between researchers.

Scilligence Partners with CAS to Optimize R&D Informatics Workflows with Scientist-Curated Data

Scilligence, a provider of web-based informatics solutions for R&D, has partnered with CAS, a division of the American Chemical Society, to enable direct access to CAS scientific content through the Scilligence informatics platform. A previous partnership between Scilligence and CAS enabled users to initiate SciFinderⁿ searches directly from Scilligence ELN (Electronic Laboratory Notebook). This new partnership builds on the previous collaboration by streamlining additional workflow scenarios. Users can now access the human-curated CAS REGISTRY^® directly from Scilligence ELN and Scilligence Inventory.

“We are excited about our second partnership with CAS. Integration of Scilligence informatics solutions with CAS content will help scientists to query and access CAS’s scientific content with more efficiency. This is an outstanding example of practicing FAIR data principles and removing data silos,” said Jinbo Lee, Chief Scientific Officer and co-founder of Scilligence.

Scilligence ELN with CAS and Scilligence Inventory with CAS are currently available with additional integrations coming in 2021 across the portfolio of products, including RegMol with CAS and TouchMol4Office with CAS. Through this integration, Scilligence users will have the ability to search for substances from CAS REGISTRY in the research workflow. CAS provides the largest and most up-to-date collection of scientific information including CAS REGISTRY, the gold standard for disclosed chemical information in the world.

“Embedding our scientist-curated data directly within Scilligence solutions will provide researchers with access to authoritative chemical names and structure data, giving them access to critical resources within their R&D workflows. This partnership is an important step to increase productivity, knowledge sharing and innovation in research,” said Andrea Jacobs, Senior Product Manager for Partnerships, CAS.

About CAS

CAS, a division of the American Chemical Society, is a specialist in scientific information that supports innovation-focused organizations globally.  For over a century, CAS products and services have enabled scientific insights to help organizations plan, innovate, protect their innovations, and hypothesize new opportunities. Built on the foundation of the CAS content collection, CAS solutions support research, patent, regulatory, and business professionals in scientific research and development. www.cas.org

About Scilligence

Scilligence is an innovation leader of web-based cheminformatics and bioinformatics solutions for life sciences R&D. The Scilligence system is built with proprietary technologies to support both biologics and small molecules in a unified platform, making it a flexible solution for a variety of research workflows. Scilligence’s informatics solutions includes a variety of modules for data management that can be utilized as separate applications or as a fully integrated system. Its tools have been widely adopted by pharmaceutical, biotech, and chemical industries, universities, research institutes, and government agencies. Scilligence is the developer of the HELM (Hierarchical Editing Language for Macromolecules) Web Editor which works to further standardize HELM notation and facilitate the exchange of information between researchers. www.scilligence.com

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CAS Media Contact:
Tina Tomeo
[email protected]

Scilligence Media Contact:
Krystyana Roman
[email protected]

In collaboration with Pistoia Alliance, Scilligence will be launching Monomer.org, a web-based platform for monomer libraries and a viewer that can interpret macromolecules expressed in a HELM string. The site, set to become available to the public in fall of 2020, will provide the scientific community with the following services:

• A well-researched and curated core monomer set to ease the deployment of the HELM ISO standard
• A secure platform to manage and share monomer libraries internally and externally
• A web portal to visualize macromolecules expressed in a HELM string

An introduction and demo to this project will be presented by Scilligence and Pistoia Alliance during our fall workshop, R&D Informatics for Special Modalities, on October 14th.

While streets and stores may be empty during the COVID-19 outbreak, our hospitals are over capacity. The COVID-19 pandemic has resulted in an increase in patients and massive shortage in supplies for healthcare workers. The world is currently facing a chronic shortage of personal protective equipment (PPE). One of these items that hospitals are in dire need of are face masks to protect workers from airborne particles. Doctors and nurses have been forced to improvise with other items because they don’t have access to proper kits.

Scilligence has responded to this need by donating 10,080 N95 face masks to the Cambridge Health Alliance. These masks help protect our healthcare heroes by providing proper filtration and facial fit to aid against contracting the novel coronavirus. Scilligence had the masks, made in the USA, shipped from overseas.

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“Their amazing gift of over 10,000 N95 masks is a critical component of our strategy to provide the greatest possible protection to our healthcare workers throughout the entire arc of this crisis.”Jill Batty, Senior Vice President and CFO of Cambridge Health Alliance.

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Scilligence is proud to be able to help support our community during these critical times. “We are saddened by the continued loss of life in this COVID-19 crisis.  This virus doesn’t distinguish between borders or race, especially endangering our healthcare workers at the frontline of this global struggle.  The donation of high-quality N95 masks to our medical community is the least we can do as a Boston-based company”, said Dr. Jinbo Lee, Chief Scientific Officer of Scilligence Corporation.  “CHA is extremely grateful for the prompt and generous outreach from Tony Yuan, Scilligence Director of R&D. This company immediately recognized the need for the Cambridge community to pull together to prepare for the COVID19 pandemic.  Their amazing gift of over 10,000 N95 masks is a critical component of our strategy to provide the greatest possible protection to our healthcare workers throughout the entire arc of this crisis. Scilligence’s willingness to step forward is a wonderful example of community stewardship during this time of crisis for the vulnerable populations CHA serves.”, said Jill Batty, Senior Vice President and CFO of Cambridge Health Alliance.

As we continue to fight this outbreak, it is important to keep in mind what we can do as groups and individuals to help this crisis come to resolution. Following guidelines and staying in unless absolutely essential is key at this time. Scilligence employees are currently working from home and assisting customers remotely. Our donation to Cambridge Health Alliance and remote efforts are a small but important part in our efforts to help end the COVID-19 pandemic.

Read on CAS Website

CAS, a division of the American Chemical Society, partnered with Scilligence to integrate SciFinderⁿ with Scilligence ELN (Electronic Laboratory Notebook). This integration helps scientists simplify their workflow by allowing easy access to vital research information in SciFinderⁿ and maintaining traceability of their ideas. Structure and reaction searches in the SciFinderⁿ content collection can be initiated directly from Scilligence ELN.

“Reference-to-idea traceability has always been a challenge for researchers due to the cumbersome nature of keeping track of reference information. As SciFinderⁿ is the leading solution used by scientists globally to search the scientific literature, the integration of SciFinderⁿ with Scilligence ELN makes this task easier for scientists, saving time and increasing productivity”, said Jinbo Lee, Chief Scientific Officer and co-founder of Scilligence

Integration of SciFinderⁿ with Scilligence ELN provides various search options directly from Scilligence ELN. Researchers can search by reaction, patent Markush, reference, substance, and supplier. Advanced algorithms developed by CAS scientists and technologists allow researchers to search smarter and find answers faster, accelerating research. The application allows users to open multiple result sets at once, and extensive filtering and Boolean search options in SciFinderⁿ help users quickly find the most relevant results.

With the SciFinderⁿ integration, scientists will have access to all the relevant information associated with their experiment within Scilligence ELN, which includes a variety of experimental templates. Users can quickly access all of the data within SciFinderⁿ with a click of a button directly from Scilligence ELN.

“CAS is committed to the continuous enhancement of scientists’ experience with SciFinderⁿ and CAS content. We welcome opportunities to more deeply integrate our solutions into our customers’ workflows to improve the effectiveness of their daily activities. The integration of SciFinderⁿ with Scilligence ELN accomplishes this by eliminating additional steps in our users’ workflow, providing actionable information more quickly and efficiently”, said Tim Wahlberg, Vice President of Product Management at CAS.

The SciFinderⁿ content collection includes millions of references, substances, reactions, properties and suppliers. Users can search references and patents with text and keywords. Substances and reactions can be searched as drawn, by substructure, and by similarity. Substances include both organic and inorganic as well as protein and nucleic acid sequences. The integration supports both single and multi-step reactions. Suppliers can be searched as drawn and include catalog items and CAS Registry Numbers^®. Users have the ability to use the Markush search to find location, filter by patent office, and access the PatentPak^® viewer.

The integration will greatly benefit researchers by giving them direct access to patent documents, step-by-step synthetic procedures and methods, and product yields right from their ELN. Researchers will be able to make better decisions with relevant knowledge and insights. CAS and Scilligence are proud to be part of a project that enhances workflows for scientists and ultimately accelerates research and look forward to further developing the integration’s features.

About CAS

CAS, a division of the American Chemical Society, partners with R&D organizations globally to provide actionable scientific insights that help them plan, innovate, protect their innovations, and predict how new markets and opportunities will evolve. Scientific researchers, patent professionals and business leaders around the world across commercial, academic and government sectors rely on our solutions and services to advise discovery and strategy. Leverage our unparalleled content, specialized technology, and unmatched human expertise to customize solutions that will give your organization an information advantage. With more than 110 years’ experience, no one knows more about scientific information than CAS. Learn more at www.cas.org.

About Scilligence

Scilligence is an innovation leader of web-based cheminformatics and bioinformatics solutions for life sciences R&D. The Scilligence system is built with proprietary technologies to support both biologics and small molecules in a unified platform, making it a flexible solution for a variety of research workflows. Scilligence’s informatics solutions includes a variety of modules for data management that can be utilized as separate applications or as a fully integrated system. Its tools have been widely adopted by pharmaceutical, biotech, and chemical industries, universities, research institutes, and government agencies. Scilligence is the developer of the HELM (Hierarchical Editing Language for Macromolecules) Web Editor which works to further standardize HELM notation and facilitate the exchange of information between researchers. www.scilligence.com

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CAS Media Contact:
Tina Tomeo
614-447-3600
[email protected]

Scilligence Media Contact
Krystyana Roman
[email protected] 
+1 (617) 520-4588

Scilligence, an innovation leader of unified informatics platform for biologics and small molecules drug R&D, has partnered with Certara to enable advanced data analysis and visualization capabilities. The companies worked together to integrate Certara’s D360 with Scilligence’s RegMol system. The partnership will help current and future clients to better visualize their scientific research data.

Scilligence provides an integrated platform for life science R&D. Scilligence’s RegMol is a web-based system for modality (small molecules, biologics, and conjugates) registration and bioassay database. Certara’s D360 provides scientists with multi-source data access tightly coupled with analysis and data visualization tools to allow efficient data-driven decision making; one click access to project data views and ad hoc data mining.

“We are very excited about the seamless integration of RegMol with D360, which provides our clients advanced data analysis and visualization options without the need of manually exporting and importing data”, said Jinbo Lee, Chief Scientific Officer and co-founder of Scilligence.

The Scilligence-Certara partnership benefits companies in drug discovery working with small molecules and biologics. By integrating their systems, the companies can improve efficiency and reduce data silos for researchers.  Scilligence and Certara look forward to continuing their partnership and exploring other areas of collaboration.

“Integration of D360 with Scilligence’s data systems allows our mutual customers to both capture and analyze research data with unprecedented efficiency allowing real-time research decision making. The creation of a standard Scilligence connector for D360 allows rapid, simple deployment of a best-of-breed system that supports research with a minimum of maintenance overhead.” said David Lowis, Senior Director of Product Management at Certara

About Scilligence

Scilligence is an innovation leader of web-based cheminformatics and bioinformatics solutions for life sciences R&D. The Scilligence system is built with proprietary technologies to support both biologics and small molecules in a unified platform, making it a flexible solution for a variety of research workflows. Scilligence’s informatics solutions includes a variety of modules for data management that can be utilized as separate applications or as a fully integrated system. Its tools have been widely adopted by pharmaceutical, biotech, and chemical industries, universities, research institutes, and government agencies. Scilligence is the developer of the HELM (Hierarchical Editing Language for Macromolecules) Web Editor which works to further standardize HELM notation and facilitate the exchange of information between researchers. www.scilligence.com

About Certara
Certara is the global leader in advancing modern, efficient drug development. Certara provides proven modeling & simulation, regulatory science, and scientific value assessment software and services to help clients reduce clinical trial burden, accelerate regulatory approval, and increase patient access to medicines. www.certara.com

Zifo RnD Solutions and Scilligence Corporation announce a strategic partnership that enables Zifo to provide System Integrations Solutions for Scilligence suite of integrated informatics solutions. The partnership will help clients to easily select, evaluate, and implement solutions that fit their research needs.

Scilligence provides the scientific community with powerful tools to mine and manage data collected in labs. Zifo will complement Scilligence by providing technology services to make different systems seamlessly connect to each other. This will ensure uninterrupted flow of data between systems, helping scientists save valuable time.

“We are excited to work together with Scilligence and strongly believe the value addition we can provide together to the end user would be tremendous,” said Raj Prakash, CEO and Co-Founder of Zifo RnD Solutions.

“The Zifo team has done an excellent job supporting Scilligence’s informatics platform at a few big pharma and large biotech companies. This partnership will strengthen our collaborations and enhance quality of informatics services to life science community,” said Jinbo Lee, CSO and Co-Founder of Scilligence Corporation.

About the Partners
Scilligence is an innovation leader of web-based cheminformatics and bioinformatics solutions for both small molecules and biologics. As the developer of the HELM (Hierarchical Editing Language for Macromolecules) Web Editor, Scilligence works with Pistoia Alliance to further standardization of HELM notation for macromolecules. Scilligence’s one-stop-shop for R&D informatics needs includes a variety of modules for data management that can be utilized as separate applications or as a fully integrated system. Its tools have been widely adopted by pharmaceutical, biotech, and chemical industries, universities, research institutes, and government agencies. Visit: www.scilligence.com to learn more.

Zifo RnD Solutions is a fast-growing global organization with offices in US, UK, India, France, China and Japan. Zifo RnD Solutions helps organizations strategize, design, implement and support their systems by providing solutions in Laboratory Informatics, Scientific Data Management, Clinical Biometrics, Genome Informatics and Compliance Solutions.

Zifo works with customers from more than 20 countries, including 7 of the Top 10 global Bio-Pharmas. It has been ranked as one of the Fastest Growing Technology Companies for 7 consecutive years (2012 – ’18) by Deloitte, and has been recognized as one of the Best Companies to Work For in India 2016 by the Great Place to Work Institute and as one of India’s Great Mid-Size Workplaces – 2017, 2018 & 2019 – A study conducted by Great Place to Work® Institute India. Visit: www.zifornd.com to learn more.

From the inception of the company, HitGen has been utilizing Scilligence’s Electronic Laboratory Notebook (ELN) and RegMol (Registration and BioAssay) system to capture and manage the large volume of DEL (DNA-encoded libraries) and their drug discovery project data.

“I was very impressed by the CEO of HitGen Dr. Jin Li’s vision that he would establish an integrated informatics platform before the first data point was generated at his company”, said Dr. Jinbo Lee, CSO of Scilligence Corporation.

“Scilligence provided HitGen an effective data management system in the early days of company’s development history, which has been useful in supporting our research activities”, said Dr. Jin Li, CEO of Hitgen.

About HitGen

HitGen is an integrated drug discovery company focused on the on the design, synthesis, and screening of DNA encoded chemical libraries (DELs). HitGen’s DELs contain over 400 billion novel, diverse, drug-like small molecule and macrocyclic compounds. These compounds are members of DELs synthesized from many hundreds of distinct chemical scaffolds, designed with tractable chemistry, and yielded proven results for the discovery of small molecule leads against precedented and unprecedented classes of biological targets.

About Scilligence

Scilligence is a leading innovator of web-based cheminformatics and bioinformatics solutions designed for any device, browser, and platform. Scilligence’s tools enhance the knowledge sharing and productivity of researchers in discovery and development of small molecule and biologic therapeutics.

Scilligence and TetraScience announce a new integration between their products to automate data management across R&D workflows. The integration will automatically collect data from instruments, software, and other sources via TetraScience’s Data Integration Platform and then enter that data into Scilligence’s suite of informatics solutions, most notably Scilligence ELN (Electronic Laboratory Notebook), RegMol (Compound Registration and Bioassay System) and Scilligence SDMS (Scientific Data Management System), three of its flagship products.

“The partnership with Scilligence aligns with our core beliefs that science should be a connected ecosystem driven to bring the best-of-breed applications together,” says Siping Wang, Co-Founder and CEO of TetraScience. “Through this new integration, we believe that we are further empowering every scientist to do more science while not limiting the instruments and software that they choose to use.”Moving R&D ForwardScilligence and TetraScience provide solutions that are designed to unlock the value of data collected in the lab environment. Paired together, Scilligence ELN, RegMol, and SDMS will be automatically populated with important data gathered by TetraScience, all with a few clicks of a button. By lessening the amount of time scientists spend working to input data, the integration will improve data integrity, increase efficiency, and begin to lay the foundation for any machine-learning and AI initiatives.“We are excited to join forces with TetraScience to provide better experiences and value to scientists in life sciences research,” says Jinbo Lee, Co-Founder and CSO of Scilligence Corporation. “This integration of technologies can not only provide significant time saving but also better data quality and regulatory compliance.”The PartnersAbout ScilligenceScilligence is an innovation leader of web-based cheminformatics and bioinformatics solutions for both small molecules and biologics. The Scilligence system is platform agnostic and modularized.  Its tools have been widely adopted by pharmaceutical, biotech, and chemical industries, universities, research institutes, and government agencies. Scilligence is the developer of the HELM (Hierarchical Editing Language for Macromolecules) Web Editor which works to standardize notation for biologics and facilitate the exchange of information between researchers. Visit: www.scilligence.com to learn more.About TetraScienceTetraScience is a Data Platform for Life Sciences R&D. Their technology helps life science companies advance discovery through insights into lab operations and comprehensive data integration. With TetraScience, laboratories connect critical information sources from instruments and lab systems to a cloud-based data platform. Data is centralized and standardized and available to downstream targets resulting in improved data management and streamlined process. In addition, TetraScience builds lab operation applications including Lab Monitoring via IoT technology and Lab Scheduling software. Visit www.tetrascience.com to learn more.DisclaimerThe statements in this press release that relate to future plans, events or performance are forward-looking statements that involve risks and uncertainties, including risks associated with uncertainties related to contract cancellations, developing risks, competitive factors, uncertainties pertaining to customer orders, demand for products and services, development of markets for the Company’s products and services. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to release publicly the result of any revisions to these forward-looking statements that may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.All product and service names mentioned are the trademarks of their respective companies.

Princeton University has licensed Scilligence Electronic Laboratory Notebook (ELN) and Inventory for Chemistry. The Scilligence platform has been deployed department-wide to support the university’s research efforts. “The Scilligence ELN system has greatly streamlined the users work by providing state-of-the-art tools and intuitive functionality. Also, the ability to be platform agnostic has greatly enhanced the experience in our heavily mixed environment. Finally, the support we have received is nothing short of exceptional. Very competent and friendly.” said Douglas Rosso, Senior IT Manager, Chemistry, Princeton University.

About Princeton University
Princeton University is a private Ivy League research university in Princeton, New Jersey. Founded in 1746 in Elizabeth as the College of New Jersey, Princeton is the fourth-oldest institution of higher education in the United States and one of the nine colonial colleges chartered before the American Revolution. Princeton University Chemistry was founded in 1795 and is one of the oldest departments of chemistry in the country.